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Endometrial cancer

Definition
  • Cancer of the endometrium
  • 75% of cases are post-menopausal
Risk Factors
  • Obesity
  • Nulliparity
  • Unopposed estrogen
  • Combination oral contraceptives
  • Family history
Differential diagnosis

Epidemiology
  • Most frequently occurring female genital cancer
  • Approximately 40,100 cases of corpus cancer were predicted to occur in the United States in 2008
  • Mortality is higher in black women than in white women
Aetiology

Clinical features
  • Abnormal vaginal bleeding
    • Frequently postmenopausal
  • No gross evidence of disease on the cervix and with a normal-sized uterus
Pathophysiology

Investigations
  • Vaginal ultrasonography
  • Hydroultrasonography
  • Endometrial biopsy
Management

a) conservative

b) medical

c) surgical

Prognosis

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