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Osteomyelitis

Definition
  • Infection of the bone or bone marrow
  • Clasified based on
    • Causative organism (pyogenic bacteria or mycobacteria)
    • Route, duration and anatomic location of the infection
Risk Factors
  • Sickle cell anaemia
Differential diagnosis

Epidemiology

Aetiology
Clinical features
  • Pain
Pathophysiology
  • Leukocytes invade
  • Release enzymes which destroy the bone
  • Pus entry -> imparied perfusion
  • Necrosis
Investigations
  • Xray will reveal abcesses in bone as radiolucency
  • Blood / bone culture
Management

a) conservative



b) medical
  • Antibiotics
c) surgical



Prognosis
  • May develop to chronic condition
  • Chronic osteomyelitis may be due to the presence of intracellular bacteria
    • Therefore resistant to antibiotics
  • In infants, the infection can spread to the joint and cause arthritis
  • In children, large subperiosteal abscesses can form because the periosteum is loosely attached to the surface of the bone
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