Antihistamines- First-generation (sedating)
- Diphenhydramine
- Chlorphenamine
- Second-generation
- Third-generation
- Levocetirizine
- Fexofenadine
Mirtazapine - Noradrenergic and specific serotonergic antidepressant (NaSSA)
- Primary use is the treatment of major depressive disorder and other mood disorders
- Also useful in anxiety, panic, PTSD, insomnia..
- Comparable efficacy and tolerability to SSRIs and SNRIs
- Side effects:
- Somnolence (54%)
- Weight gain (≥7% weight gain, only in paediatrics is this very common − incidence=49%)
- Dry mouth (25%)
- Increased appetite (17%)
- Constipation (13%)
Dr MCQ Bravado- Dr - define risk
- Justify why they are on a CTG
- M - movements
- C - contractions
- Are there any and how often
- Q - quality
- How good is the trace, is there lots of loss of contact? can you read it?
- Bra - baseline rate
- V - variability
- Should be between 5 and 15bpm
- A - accelerations
- A rise of 15bpm or more for more than 15 seconds - a good sign
- D - decelerations
- A drop of 15bpm or more for more than 15seconds
- O - overall and plan
Asthma review questions - Difficulty sleeping due to symptoms
- Day symptoms
- Exercise tolerance
MRCP dyspnoea scale - Not troubled by breathlessness except on strenuous exercise
- Short of breath when hurrying or walking up a slight hill
- Walks slower than contemporaries on the level because of breathlessness, or has to stop for breath when walking at own pace
- Stops for breath after about 100 m or after a few minutes on the level
- Too breathless to leave the house, or breathless when dressing or undressing
Heart failure (EF<40%) - Medications- ACE-i/ARB reduce mortality and morbidity in patients with heart failure and left ventricular systolic dysfunction
- β-blockers reduce mortality and morbidity in patients with heart failure and left ventricular systolic dysfunction
- β-blockers specifically shown to reduce mortality and morbidity in HF with LVSD are carvedilol, metoprolol, bisoprolol
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