Rheumatoid Arthritis Associations
- Eyes
- Secondary Sjögren's syndrome
- Scleritis
- Episcleritis
- Skin
- Leg ulcers
- Felty's syndrome
- Rashes
- Nail fold infarcts
- Rheumatoid nodules
- May occur in the eyes, may be subcutaneous, and may be in the lung, heart and occasionally the vocal cords
- Neurological
- Peripheral nerve entrapment
- Atlanto-axial subluxation
- Polyneuropathy
- Mononeuritis multiplex
- Respiratory
- Pleural involvement
- Pulmonary fibrosis
- Bronchiolitis obliterans
- Caplan's syndrome
- Cardiovascular
- Pericardial involvement
- Valvulitis
- Myocardial fibrosis
- Vasculitis
- MI
- Kidneys
- Analgesic nephropathy
- Amyloidosis
- Liver
- Mild hepatomegaly
- Abnormal transaminases
- Other
- Thyroid disorders
- Osteoporosis
- Depression
- Splenomegaly
SICKFACES.COM Group- Sodium valproate
- Isoniazid
- Cimetidine
- Ketoconazole
- Fluconazole
- Alcohol (acute)
- Chloramphenicol
- Erythromycin
- Sulfonamides
- Ciprofloxacin
- Omeprazole
- Metronidazole
- Grapefruit juice
Seronegative arthropathies
- Ankylosing spondylitis
- Spinal movement reduced in all directions
- Question-mark posture
- Associations: All the A's:
- Ankylosis of spine
- Acute anterior uveitis
- Amyloidosis
- Aortic incompetence
- Aortitis
- AV Block
- Apical fibrosis
- Achilles tendonitis
- Anti-TNF alpha therapy
- Psoriatic arthritis
- Reactive arthritis
- Chlamydia is the most common trigger (50%)
- Antibiotics don't help
- Enteropathic arthritis
Felty's syndrome
- Combination of rheumatoid arthritis, SPLENOMEGALY and neutropenia
- Normally after a long time with RA
- Manage by controlling the underlying RA
- Pancytopenia with bone marrow hyperplasia
- cf Hypoplasia as side-effect of medication
Notes
- Eyes
- Scleritis is PAINFUL
- Episcleritis is PAINLESS
- Keratitis is BILATERAL
- Anti-TNF alpha
- CHECK TB STATUS
- Really good for ank. spond.
- Steroids => Striae on trunk
- Brick-shaped, positive birefringent crystals in pseudogout
- SLE: ANA 95%, anti-dsDNA 80%
- Schober's test
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