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Abatacept

Class
  • Selective costimulation modulator inhibiting the costimulation of T cells
Indications
Administration/Absorption

Dosage

Distribution

Mechanism
  • Fusion protein composed of an immunoglobulin fused to the extracellular domain of CTLA-4, which can bind B7
  • Binding to the B7 protein on APCs prevents them from delivering the costimulatory signal to T cells
  • Thus prevents the full activation of T cells.[1][2]
Excretion

Side effects

Interactions

Contraindications

Comments