Class- Selective costimulation modulator inhibiting the costimulation of T cells
Indications Administration/AbsorptionDosage DistributionMechanism- Fusion protein composed of an immunoglobulin fused to the extracellular domain of CTLA-4, which can bind B7
- Binding to the B7 protein on APCs prevents them from delivering the costimulatory signal to T cells
- Thus prevents the full activation of T cells.[1][2]
ExcretionSide effectsInteractions Contraindications
|
|