ClassIndications Administration/AbsorptionDosage DistributionMechanism- Prevents H2CO3 conversion to CO2 + H2O in kidney tubules
- CO2 normally rapidly diffuses into blood
- This is the mechanism of HCO3- reabsorption in the kidney
- H2CO3 therefore leaves in the urine
- H+ taken up with Cl-
- => hyperchloremic metabolic acidosis
ExcretionSide effectsInteractions Contraindications
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