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Acetazolamide

Class
Indications
Administration/Absorption

Dosage

Distribution

Mechanism
  • Prevents H2CO3 conversion to CO2 + H2O in kidney tubules
    • CO2 normally rapidly diffuses into blood
    • This is the mechanism of HCO3- reabsorption in the kidney
  • H2CO3 therefore leaves in the urine
  • H+ taken up with Cl-
    • => hyperchloremic metabolic acidosis
Excretion

Side effects

Interactions

Contraindications

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