Kieran's Medical Notes
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Amiloride
Class
Potassium-sparing diuretic
Indications
hypertension
congestive heart failure
.
Administration/Absorption
Dosage
Distribution
Mechanism
Directly blocks the
epithelial sodium channel
(ENaC) thereby inhibiting
sodium
reabsorption in the late
distal convoluted tubules
, connecting tubules, and collecting ducts
Promotes the loss of sodium and water from the body, but without depleting
potassium
Excretion
Side effects
Interactions
Contraindications
Comments