Kieran's Medical Notes
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Amiodarone
Indications
antiarrhythmic agent
various types of tachyarrhythmias
both ventricular and supraventricular (atrial) arrhythmias
Administration/Absorption
Distribution
Mechanism
class III
antiarrhythmic agent
prolongs phase 3 of the
cardiac action potential
beta blocker
-like and
potassium channel blocker
-like actions on the
SA
and
AV nodes
increases the refractory period via sodium- and potassium-channel effects
slows intra-cardiac conduction of the
cardiac action potential
, via sodium-channel effects
Excretion
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