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Danazol

  • Derivative of the synthetic steroid ethisterone, a modified testosterone
    • Also known as 17alpha-ethinyl testosterone
  • Creates a hypoestrogenic and hyperandrogenic state
  • Decreases menstrual blood loss by 70% to 80%
  • Dosing schedule of 400 to 800 mg daily or less-traditional schedule of 50 to 100 mg daily
  • Typical side effects
    • weight gain, acne, potential alteration of lipid levels
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