Kieran's Medical Notes
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Doxazosin
Indications
high blood pressure
benign prostatic hyperplasia
Administration/Absorption
Distribution
Mechanism
alpha-1 adrenergic receptor blocker
inhibits the binding of
norepinephrine
to
alpha-1 receptors
on the membrane of vascular
smooth muscle
cells.
Relaxed vascular
smooth muscle
tone (
vasodilation
) decreases
peripheral vascular resistance
, leading to decreased
blood pressure
.
Excretion
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