Kieran's Medical Notes
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Furosemide
Indications
congestive
heart failure
edema
Administration/Absorption
Distribution
Mechanism
loop diuretic
inhibits the
Na-K-2Cl symporter
in the
thick ascending limb
of the
loop of Henle
.
The action on the distal tubules is independent of any inhibitory effect on carbonic anhydrase or aldosterone
Also abolishes the corticomedullary osmotic gradient and blocks negative as well as positive
free water clearance
.
Excretion
Side effects
hypokalemia
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