Leflunomide

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Class

Indications

Administration/Absorption

Dosage

Distribution

Mechanism

Excretion

Side effects

Symptomatic liver damage ranging from jaundice to hepatitis
Myelosuppression with leukopenia, and/or hypoplastic anemia, and/orthrombocytopenia
Infections
Anemia or bleeding episodes
Interstitial lung disease
GIT
skin reactions

Interactions

Alcohol, other DMARDs including chloroquine/hydroxychloroquine, live virus vaccines, tegafur, some tuberculostatics (rifampin and/or isoniazid), tolbutamide and warfarin

Contraindications

Comments

Kieran's Medical Notes	Search this site