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Medroxyprogesterone acetate

  • MDPA
  • Oral
    • 10 mg for 10 to 14 days each month
    • Induces a regular withdrawal bleed
    • This dosage does not provide contraception
  • Depo-Provera
    • Stops menses in most patients
    • MDPA 150 mg administered intramuscularly every 3 months
    • Approximately, 80% to 90% of patients completing 12 months of MDPA therapy become amenorrheic
  • Side effects can include weight gain, irregular bleeding, and depression.
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