Misoprostol

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Class

Indications

In people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications

Administration/Absorption

Dosage

Distribution

Mechanism

Acts upon gastric parietal cells
Inhibits the secretion of gastric acid via G-protein coupled receptor-mediated inhibition of adenylate cyclase
Leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell

Excretion

Side effects

Interactions

Contraindications

Comments

Kieran's Medical Notes	Search this site