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Prednisolone

Indications
Administration/Absorption
Distribution

Mechanism
  • corticosteroid drug
  • irreversibly binds with glucocorticoid receptors (GR) alpha and beta
    • AlphaGR and BetaGR are found in virtually all tissues with variable numbers between 3000 - 10000 per cell depending on the tissue involved
  • systemic suppression of inflammation and immune response
Excretion
  • half life 2-3 hours
  • renal excretion
Side effects
Comments