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Salmeterol

Indications
Administration/Absorption
  • proprietary "disk-styled" inhaler that releases a powdered form 
  • prescribed concurrently with a corticosteroid, such as beclomethasone
Distribution

Mechanism
  • long-acting beta-adrenoceptor agonist (LABA)
    • chain length of 11-atoms from the amine
    • bulkiness makes the compound more lipophilic and it also makes it β receptor selective
  • long duration of formoterol action occurs by the formoterol molecules initially diffusing into the plasma membrane of the lung cells
    • then slowly being released back outside the cell where they can come into contact with the beta-2 adrenoceptors
Excretion

Side effects

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