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Tenecteplase

Indications
Administration/Absorption

Dosage

Distribution

Mechanism
  • tissue plasminogen activator (tPA)
    • produced by recombinant DNA technology using an established mammalian cell line
  • derived from native t-PA by modifications at three sites of the protein structure
  • higher fibrin specificity and greater resistance to inactivation by its endogenous inhibitor (PAI-1) compared to native t-PA.
Excretion

Side effects

Interactions

Contraindications

Comments