Indications Administration/AbsorptionDosage DistributionMechanism- tissue plasminogen activator (tPA)
- produced by recombinant DNA technology using an established mammalian cell line
- derived from native t-PA by modifications at three sites of the protein
structure
- higher fibrin specificity and greater resistance to inactivation by its
endogenous inhibitor (PAI-1) compared to native t-PA.
ExcretionSide effectsInteractions Contraindications
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