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Tranexamic acid

  • Synthetic derivative of the amino acid lysine
  • Commonly marketed in tablet form as Lysteda and in IV form as Cyklokapron in the U.S. and as Transamin,Transcam in Asia, and Espercil in South America
  • Antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin
  • Fibrin is the basic framework for the formation of a blood clot in hemostasis
  • Has roughly 8 times the antifibrinolytic activity of an older analogue, ε-aminocaproic acid
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