Osteomyelitis

Definition

    • Infection of the bone or bone marrow

    • Clasified based on

      • Causative organism (pyogenic bacteria or mycobacteria)

      • Route, duration and anatomic location of the infection

Risk Factors

    • Sickle cell anaemia

Differential diagnosis

Epidemiology

Aetiology

Clinical features

    • Pain

Pathophysiology

    • Leukocytes invade

    • Release enzymes which destroy the bone

    • Pus entry -> imparied perfusion

    • Necrosis

Investigations

    • Xray will reveal abcesses in bone as radiolucency

    • Blood / bone culture

Management

a) conservative

b) medical

    • Antibiotics

c) surgical

Prognosis