Acetazolamide

Class

Indications

Administration/Absorption

Dosage

Distribution

Mechanism

    • Prevents H2CO3 conversion to CO2 + H2O in kidney tubules

      • CO2 normally rapidly diffuses into blood

      • This is the mechanism of HCO3- reabsorption in the kidney

    • H2CO3 therefore leaves in the urine

    • H+ taken up with Cl-

      • => hyperchloremic metabolic acidosis

Excretion

Side effects

Interactions

Contraindications