Medroxyprogesterone acetate

    • MDPA

    • Oral

      • 10 mg for 10 to 14 days each month

      • Induces a regular withdrawal bleed

      • This dosage does not provide contraception

    • Depo-Provera

      • Stops menses in most patients

      • MDPA 150 mg administered intramuscularly every 3 months

      • Approximately, 80% to 90% of patients completing 12 months of MDPA therapy become amenorrheic

    • Side effects can include weight gain, irregular bleeding, and depression.