Montelukast

Class

• Leukotriene receptor antagonist

Indications

• • Asthma (non-acute)

• seasonal allergies

Administration/Absorption

• • Oral

Dosage

Distribution

Mechanism

• CysLT₁ antagonist

  • blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT₁

Excretion

Side effects

• gastrointestinal disturbances, hypersensitivity reactions, sleep disorders and increased bleeding tendency

Interactions

Contraindications