Rituximab

Class

Indications

Administration/Absorption

Dosage

Distribution

Mechanism

  • Destroys both normal and malignant B cells that have CD20 on their surfaces

  • binds to the cluster of differentiation 20 (CD20) molecule

  • Affects and entirely depletes peripheral B cells

  • Only depletes 60-70% of B cells within in the lymphatics system

  • Rarely affects those present in the bone marrow.

Excretion

Side effects

    • Severe infusion reactions

Interactions

Contraindications