Nicotinic acid

Indications

• • Hypercholesterolemia

• atherosclerosis

Administration/Absorption

Distribution

Mechanism

• blocks the breakdown of fats in adipose tissue

• thus causes a decrease in free fatty acids in the blood

• as a consequence, decreases the secretion of VLDL and cholesterol by the liver

• By lowering VLDL levels, niacin also increases the level of high-density lipoprotein

Excretion