Bendroflumethiazide

Indications

Dosage

Administration/Absorption

    • Absorbed relatively rapidly after oral administration

Distribution

    • 96% protein bound

Mechanism

    • Thiazide diuretic

    • Vasodilation

      • Mechanism unclear

        • Activating calcium-activated potassium channels (large conductance) in vascular smooth muscles?

        • Inhibiting various carbonic anhydrases in vascular tissue?

    • Thiazides also cause an increase in serum uric acid

Excretion

    • Half life 8.5 hrs

Side effects

Interactions

Contraindications