Abatacept

Class

  • Selective costimulation modulator inhibiting the costimulation of T cells

Indications

Administration/Absorption

Dosage

Distribution

Mechanism

  • Fusion protein composed of an immunoglobulin fused to the extracellular domain of CTLA-4, which can bind B7

  • Binding to the B7 protein on APCs prevents them from delivering the costimulatory signal to T cells

  • Thus prevents the full activation of T cells.[1][2]

Excretion

Side effects

Interactions

Contraindications