Adalimumab

Class

• TNF inhibitor

Indications

• rheumatoid arthritis

• psoriatic arthritis

• ankylosing spondylitis

• Crohn's disease

• moderate to severe chronic psoriasis

• juvenile idiopathic arthritis

Administration/Absorption

• • subcut injection

Dosage

Distribution

Mechanism

• binds to TNFα, preventing it from activating TNF receptors

• constructed from a fully human monoclonal antibody

Excretion

Side effects

• Reactivation of latent infections such as tuberculoses

• Immune system may be unable to fight new infections

Interactions

Contraindications