Fondaparinux

Indications

• • Thrombosis

Administration/Absorption

• • subcutaneously

Dosage

Distribution

Mechanism

• • synthetic pentasaccharide Factor Xa inhibitor

  • anticoagulant

    • chemically related to low molecular weight heparins

  • forms the high affinity binding site for the anti-coagulant factor antithrombin III (ATIII).

    • Binding to ATIII has been shown to increase the anti-coagulant activity of antithrombin III 1000 fold.

Excretion

Side effects

Interactions

Contraindications