myocardial infarction with ST-elevation (STEMI)
acute ischemic stroke (AIS)
acute massive pulmonary embolism
central venous access devices (CVAD)
Recombinant tissue plaminogen activator
catalyzes the conversion of plasminogen into plasmin by cleaving the single-chain plasminogen into two chains
These two chains are linked by a disulfide bond and the resulting molecule is called plasmin.